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  • A multivalent signal-transducing model for the DNMT1-mediated maintenance DNA methylation

    Authors
    Wang, Gang G.
    Grimm, Sara A.
    Description

    Summary from the GEO: "Heterochromatin-specific histone modifications frequently coexist with mammalian DNA methylation to orchestrate a repressive chromatin state. However, it remains elusive how these epigenetic modifications crosstalk. Here, we report that the first bromoadjacent homology (BAH1) domain and the replication foci targeting sequence (RFTS) of maintenance DNA methyltransferase DNMT1...

    Subject
    DNA (Cytosine-5-)-Methyltransferase 1
    DNA Methylation
    Heterochromatin
    Histone Code
    Histones
    Access Rights
    Free to All
  • Crystal structure of bovine DNMT1 BAH1 domain in complex with H4K20me2

    Authors
    Ren, Wendan
    Song, Jikui
    Description

    This deposit in the Research Collaboratory for Structural Bioinformatics Protein Data Base (PDB) includes x-ray diffraction data used for modeling the crystal structure of bovine DNMT1 BAH1 domain in complex with H4K20me2. The main summary display for this entry includes information on the experimental data, validation, macromolecules, small molecules, version history and funding identification. Data...

    Subject
    DNA (Cytosine-5-)-Methyltransferase 1
    Histones
    Methyltransferases
    Repressor Proteins
    Access Rights
    Free to All
  • Crystal structure of bovine DNMT1 BAH1 domain in complex with H4K20me3

    Authors
    Ren, Wendan
    Song, Jikui
    Description

    This deposit in the Research Collaboratory for Structural Bioinformatics Protein Data Base (PDB) includes x-ray diffraction data used for modeling the crystal structure of bovine DNMT1 BAH1 domain in complex with H4K20me3. The main summary display for this entry includes information on the experimental data, validation, macromolecules, small molecules, version history and funding identification. Data...

    Subject
    DNA (Cytosine-5-)-Methyltransferase 1
    Histones
    Methyltransferases
    Repressor Proteins
    Access Rights
    Free to All